Mathematical Biology

Speaker: 
Dr. Reginald L. McGee
Speaker Affiliation: 
Haverford College

February 11, 2026

ESB 4133
2207 Main Mall
Vancouver, BC V5H4L8
Canada

I’m excited to announce our next Math-Bio seminar, happening next Wednesday, February 11th, at 2:00 pm (Pacific Time) in the PIMS lounge (ESB 4133). PIMS tea will follow the seminar at around 3:00 pm.

Our speaker will be Dr. Reginald L. McGee, an Associate Professor at the Haverford College. This talk will be done in-person, your presence will benefit immensely the event.

If you cannot make to the seminar join us through zoom:

https://ubc.zoom.us/j/65246006268?pwd=vFrUpDrzPEYGZ3dSezvCp2uiupsdiO.1

Meeting ID: 652 4600 6268

Passcode: 988036

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Abstract: 

Sickle cell pain presents in acute episodes in pediatric patients, as opposed to the chronic pain observed in adults. The episodic nature of pain events in pediatric patients necessitates a distinct approach from what has been used to mathematically model pain severity levels in adults. Statistical studies have examined interactions between measurements on sleep --- like sleep quality and sleep efficiency --- and pain levels in pediatric populations, and we propose a framework for modeling pediatric pain dynamics that incorporates the effects of patient survey data over varying time windows. We hypothesize that cumulative effects of these measurements will be more important than daily measurements in both replicating pain severity levels and determining markers of a pain episode. The ability to identify markers preceding the onset of a pain episode will be crucial in improving patient quality of life. We present work towards developing this modeling framework and a parameterization strategy to fit aggregate data for subpopulations of patients defined by age and course of treatment.

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