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Last updated: Nov 1, 2007
Publications from 2006-2007
Articles Published/Accepted in Refereed Publications
Atkinson LL, Benkoczi C, Finegood DT, McDonald-Dyck C
(2007)Effect of Chronic Rosiglitazone, Metformin and Glyburide Treatment on
Beta-Cell Function and Insulin Sensitivity in ZDF Rats. Diabetes,
Obesity, Metabolism (In press)
Ball CL, Gilchrist MA, Coombs D (2007) Modeling within-host evolution of HIV: Mutation, competition and strain replacement. Bull Math Biol, doi:10.1007/s11538-0
07-9223-z
Bernard S, Cajavek B, Pujo-Menjouet L, Mackey MC, Herzel H (2006) Modeling
transcriptional feedback loops: The role of Gro/TLE1 in Hes1 oscillations,
Proc Roy Soc Lond 364:1155-1170.
Colijn C, Fowler AC, Mackey MC (2006) High frequency spikes in long
period blood cell oscillations. J Math Biol 53:499-519.
Colijn C, Fowler AC, Mackey MC (2007) G-CSF treatment of canine
cyclical neutropenia: A comprehensive mathematical model. Exper
Hematol 35:898-907.
Colijn C, Mackey MC (2007) Bifurcation and bistability in a model of
hematopoietic regulation. SIAM J App Dynam Sys 6:378-394.
Colijn C, Dale DC, Foley C, Mackey MC (2007) Observations on the
Pathophysiology and mechanisms for Cyclic Neutropenia. Math Model
Natur Phenomena (in press).
Coombs D, Gilchrist MA, Ball CL (2007) Resolving the importance of within- and between-host selection pressures on pathogen evolution. J Theor Biol, doi:10.1016
/j.tpb.2007.08.005
Cytrynbaum EN, Marshall B (2007) A Polymer Model Explains MinDE
Dynamics in E. coli Cell Division. Biophys J, 93:1134-1150.
Dawes AT, Edelstein-Keshet L (2007) Phosphoinositides and Rho proteins spatially
regulate actin polymerization to initiate and maintain directed movement in a 1D model
of a motile cell, Biophys J. 92:1-25.
Drobnjak I, Fowler AC, Mackey MC (2006) Oscillations in a maturation
model of blood cell production. SIAM J Appl Math 66:2027-2048.
Dushek O, Coombs D (2007) Improving parameter estimation for cell surface FRAP d
ata. J Biochem Biophys Meth, doi:10.1016/j.jbbm.2007.07.002
Dushek O, Coombs D (2006) Analysis of serial engagement and peptide-MHC
transport in T cell receptor microclusters. Accepted (minor rev.).
Glover CH, Marin M, Eaves CJ, Helgason CD, Piret JM, Bryan J (2006)
meta-analysis of mouse embryonic stem cell gene
expression kinetics reveals consistent early change of a small gene set
under differentiating conditions,
PLoS Computational Biology, 2(11) e158.
Jilkine A, Maree AF, Edelstein-Keshet L (2007) Mathematical model for
spatial segregation of the rho-family GTPases based on inhibitory
crosstalk.
Bull Math Biol. 69(6):1943-78.
Konorov, SO, Glover CH, Piret JM, Bryan J, Schulze HG, Blades MW,
Turner RFB (2007) In Situ Coherent Anti-Stokes Raman
Microscopy of Living Embryonic Stem Cells, Analytical Chemistry, in press.
Lei J, Mackey MC (2007) Stochastic differential delay equation,
moment stability, and application to hematopoietic stem cell
regulation system. SIAM J App Math 67:387-407.
Lu M, Glover CH, Humphries RK, Piret JM and Helgason CD (2007) Involvement of tyrosine kinase signaling in maintaining
murine embryonic stem cell functionality, Experimental Hematology, in press.
Mackey MC (2007) Adventures in Poland: Having fun and doing research
with Andrzej Lasota. Matematyka Stosowana 8:5-32.
Mahaffy JM, Edelstein-Keshet L (2006) Modeling cyclic waves of circulating T-cells in
autoimmune diabetes, SIAM J Appl Math 67 (4): 915-937.
Maree AFM, Komba M, Finegood DT, Edelstein-Keshet L (2007) A
Quantitative Comparison of Rates of Phagocytosis and Digestion of
Apoptotic Cells by Macrophages from Normal (Balb/C) and
Diabetes-prone (NOD) Mice. Journal of Applied Physiology, accepted.
Mori Y, Peskin CS (2007) Implicit Immersed Boundary Methods with Boundary
Mass. Comp Meth Appl Mech Eng, accepted.
Mori Y (2007) Convergence Proof of the Velocity Field of a
Stokes Flow Immersed Boundary Method. Comm Pure Appl Math,
accepted.
Rodriguez-Gonzalez JG, Santillan M, Fowler AC, Mackey MC (2007) The
segmentation clock in chick and mice: Interaction with a Wnt3a
gradient. J Theor Biol (in press).
Santillan M, Mackey MC, Zeron ES (2007) Origin of bistability in the
lac operon. Biophy J 92:3830-3842.
Topp BG, Atkinson LL, Finegood, DT (2007) The Dynamics of
Insulin Sensitivity, Beta-Cell Function, and Beta-Cell Mass During
the Development of Diabetes in fa/fa Rats. Am J Physiol:
Endocrinology & Metabolism (In press).
Other published refereed contributions
Finegood DT, Komba M, Atkinson L(2007) Apoptosis, phagocytosis
and beta-cell directed Autoimmunity. (Commentary on article
[Neonatal beta-cell apoptosis: A trigger for autoimmune
diabetes??]) Commentaries on Perspectives in Diabetes, Vol 3.
Published non-refereed contributions:
Theses
Raluca Apostu (MSc McGill, 2007) Understanding cyclical thrombocytopenia: A
mathematical modeling approach. (Supervisor: M Mackey)
Kevin Davis (PhD McGill 2007) An analysis of models of the tryptophan operon
(Supervisor: M Mackey)
Clive Glover (PhD UBC 2007) Genetics Ph.D. thesis:
New Approaches to the Optimized Maintenance of Embryonic Stem Cells in
Culture (Supervisor: Jamie Piret)
Ozge Karanfil(MSc. McGill 2007) A mathematical model of steady state B lymphopoiesis
in mouse and rat bone marrow (Supervisor: M Mackey)
Mitsu Komba (MSc SFU 2007) Extracellular release of high mobility group box1 protein from necrotic beta-cells in pathogenesis of type 1 diabetes mellitus. (Supervisor: Diane Finegood)
Conference Proceedings:
Coombs D, Ball CL, Gilchrist MA (2007) Competition among viruses at the within-
and between-host scales. (Conference proceedings, Nonlinear Theory and Applications 2007, Vancouver).
Articles Submitted to Refereed Publications
Das R, Nachbar RB, Salzman JS, Bagchi A, Bailey J, Edelstein-Keshet L,
Coombs D, Cook J, Hargreaves R, Simon A (2007) Modeling the effect of
gamma-secretase on amyloid-beta dynamics revelas significant role of an amyloid clearance mechanism, imminent submission.
Dushek O, Bailey J, Coombs D (2007) Predicting the effects of dual T cell receptor T cells on autoimmunity and the immune repertoire. Submitted.
Dushek O, Das R, Coombs D (2007) Analysis of membrane-localized binding kinetics
with FRAP. Submitted.
Khadra A, Li YX (2006) Robust synchrony and rhythmogenesis in endocrine
neurons via autocrine regulations in vitro and in vivo. Submitted.
Khadra A, Li YX (2007) Theoretical analysis of neuronal synchrony driven by
common pool of extracellular hormone, submitted to Physica D.
Mori Y (2006) A Three Dimensional Model of Cellular Electrical Activity: An
Asymptotic Study. Submitted
Mori Y, Peskin CS (2007) A Numerical Method of Celllular Electrophysiology
based on the Electrodiffusion Equations with Internal Boundary Conditions at
Membranes. Submitted
Mori Y, Peskin CS (2007) On the Representation of a General Incompressible
Linearly Elastic Material as a Fiber-Reinforced Fluid. Submitted
Mori Y, Fishman GI, Peskin CS (2007) Ephaptic Conduction in a
Three-Dimensional Model of the Intercalated Disc. Submitted
Mori Y, Jilkine A, Edelstein-Keshet L (2007) Wave-pinning and cell polarity from a bistable reaction-diffusion system, submitted
In preparation:
Borowski P, Cytrynbaum EN (2007) MinD phenotypes in filamentous
mutants.
Chaudhry MAS, Bowen BD, Eaves CJ, Piret JM Medium pH and osmolality
influence the proliferation and differentiation responses of murine
embryonic stem cells, to be submitted to Biotechnology Progress, 90%
complete.
Chaudhry MAS, O'Connor M, Bowen BD, Eaves CJ, Piret JM, Basal medium and
serum substitutes influence the proliferation and differentiation of
murine embryonic stem cells, to be submitted to Cytotechnology, 90%
complete
Cytrynbaum EN, Lewis TJ (2007)Global bifurcations and the appearance
of a one-dimensional spiral-wave in excitable media.
Mori Y (2007) Convergence of the Immersed Boundary Method and the Even-Odd
Condition.
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