%% Estimate asymptotic confidence intervals for a nonlinear regression %% fit using nlparci (Statistics toolbox) %% Fit simulated dose-response data to a Hill function, given by %% y(x) = ymax/(1 + (EC50/dose)^n) %% Load data DoseResponse = load('DoseResponseData.dat', '-ascii'); dose = DoseResponse(:,1); yExpt = DoseResponse(:,2); %% Call nlinfit to perform nonlinear regression. betaGuess = [1, 1, 1]; % Initial guess for parameter values [betaHat, res, Jac, Cov, mse] = nlinfit(dose, yExpt, @Hill, betaGuess); %% Supply output to nlparci to estimate asymptotic 95% CIs. asympCI = nlparci(betaHat, res, 'covar', Cov); %% Print parameter estimates and asymptotic CIs [betaHat' asympCI]