## Math 561, Section 201:
Mathematics of Infectious Diseases and Immunology

`http://www.math.ubc.ca/~coombs/561/math561.html`

Instructor: Dr. Daniel Coombs.

Office: Mathematics Annex, Room 1109.

Email: coombs (at) math (dot) ubc (dot) ca

Phone: 604-822-2859

Class hours: 2pm-3.20pm, Tuesday and Thursday.

### Topics

**Models for disease spread and pathogen evolution:**
Basic concepts of mathematical epidemiology for simple and for structured populations. We will also
review some concepts of pathogen evolution. The best book on this topic is Diekmann and Heesterbeek.

**Virus dynamics modeling:**
Development of virus models from experimental data; model analysis;
implications for epidemic models.

**Immune system models:**
Antigen detection by antibodies and receptors. T cell activity and
immune synapse. Cell adhesion, ligand binding.
### Activities

Final grades will be assigned roughly as follows:
Homework 35%, Paper presentation and written summary 15%, project proposal 5%,
project 35%, participation in class 10%.
There will be homework sets.
Each student will choose a paper from the reading list, present the
main results of that paper in class and write a 3-page summary/review
with discussion.
A final project will be proposed by the students (probably in
groups), written up, and presented.

Daniel Coombs
/ Department of Mathematics /
University of British Columbia