Rhodin J; Thomas T; Bryant M; Sutton ET.
Animal model of Alzheimer-like vascular pathology and inflammatory reaction, Ann N Y Acad Sci 903 :345-52, 2000.
Abstract
This in vivo animal model of vascular inflammatory reaction facilitates morphologic and hemodynamic analyses of leukocyte-endothelial interaction and can be monitored by video microscopy and electron microscopy. The model has served as a rapid means to explore the deleterious vascular actions and inflammatory response to the cytokines tumor necrosis factor, interleukin-1 and amyloid-beta, as well as the protective effects of superoxide dismutase, estrogen, and cytokine antagonists
Return to Neurotoxicity of Cytokines References